Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.40 |
| ▸ | CDK2 | P24941 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CCNO | P22674 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12759737 | 0.72 | MEN1 (0.47) | SMN1; SMN2MAPTALDH1A1THRBTDP1 | |
| SCHEMBL18949733 | 0.71 | ALDH1A1 (0.55) | SMN1; SMN2MAPTALDH1A1THRBTDP1 | |
| SCHEMBL22304735 | 0.70 | MAPT (0.48) | SMN1; SMN2MAPTALDH1A1THRBTDP1 | |
| SCHEMBL31436278 | 0.70 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTALDH1A1TDP1RAB9A | |
| SCHEMBL9027066 | 0.69 | CCNA2 (0.35) | CCNA2CDK2FLT3LMNA | |
| SCHEMBL9026693 | 0.69 | MAPT (0.43) | SMN1; SMN2MAPTALDH1A1THRBTDP1 | |
| SCHEMBL12335145 | 0.69 | MAPT (0.66) | SMN1; SMN2MAPTALDH1A1THRBTDP1 | |
| SCHEMBL20320460 | 0.68 | MAPK10 (0.46) | SMN1; SMN2MAPTALDH1A1THRBTDP1 | |
| SCHEMBL21198443 | 0.68 | RAB9A (0.42) | SMN1; SMN2MAPTALDH1A1THRBTDP1 | |
| SCHEMBL29672466 | 0.68 | RAB9A (0.42) | SMN1; SMN2MAPTALDH1A1THRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5220028-A | Halogeno-4-methylpyrazoles | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1993-06-15 | — | — | US | claimed |
| EP-0366329-B1 | Halogeno-4-methylpyrazoles and process for preparing the same | NISSAN CHEMICAL IND LTD (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5220028-A | Halogeno-4-methylpyrazoles | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0366329-A1 | Halogeno-4-methylpyrazoles and process for preparing the same | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1990-05-02 | — | — | EP | disclosed |