Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GRM8 | O00222 | 3/20 | 0.36 |
| ▸ | GRM6 | O15303 | 3/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629582 | 0.94 | KMT2A (0.46) | ALDH1A1KMT2AMEN1HPGDL3MBTL1 | |
| SCHEMBL8630297 | 0.87 | PFKFB3 (0.38) | ALDH1A1PFKFB3TSHRRECQL | |
| SCHEMBL31067589 | 0.80 | ALDH1A1 (0.68) | ALDH1A1KMT2AMEN1HPGDL3MBTL1 | |
| SCHEMBL17065068 | 0.80 | ALDH1A1 (0.68) | ALDH1A1KMT2AMEN1HPGDL3MBTL1 | |
| SCHEMBL8631276 | 0.72 | BRD4 (0.41) | KMT2AMEN1ACP3 | |
| SCHEMBL8634093 | 0.72 | BRD4 (0.43) | ACHE | |
| SCHEMBL17064903 | 0.72 | ALOX5 (0.47) | ALDH1A1KMT2AMEN1HPGDL3MBTL1 | |
| SCHEMBL17064674 | 0.70 | CA1 (0.56) | ALDH1A1KMT2AMEN1LMNAMAP2K1 | |
| SCHEMBL8631320 | 0.70 | ALDH1A1 (0.37) | ALDH1A1LMNATSHRMAPTSMN1; SMN2 | |
| 3-Nitroaniline SCHEMBL28807505 | 0.69 | ALDH1A1 (0.88) | ALDH1A1KMT2AMEN1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707574-A1 | NOVEL (1-PHENYL-1-HETEROCYCLYL)METHANOL AND (1-PHENYL-1-HETEROCYCLYL)METHYLAMINE DERIVATIVES | Astra Aktiebolag (SE) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001968-A1 | NOVEL (1-PHENYL-1-HETEROCYCLYL)METHANOL AND (1-PHENYL-1-HETEROCYCLYL)METHYLAMINE DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1995-01-19 | — | — | WO | disclosed |