Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 15/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026598 | 1.00 | EIF4E (0.41) | EIF4EMAPTTHRBABL1TP53 | |
| SCHEMBL9027817 | 0.87 | MAPT (0.43) | MAPTTP53KDM4EGAARECQL | |
| SCHEMBL9029172 | 0.83 | KDM4E (0.33) | EIF4EMAPTKDM4E | |
| SCHEMBL9027940 | 0.83 | MAPT (0.46) | MAPTTHRBABL1KDM4E | |
| SCHEMBL9028092 | 0.80 | TP53 (0.43) | MAPTTP53KDM4EGAARECQL | |
| SCHEMBL9029323 | 0.79 | MAPT (0.41) | EIF4EMAPTTHRBTP53KDM4E | |
| SCHEMBL9028732 | 0.77 | EIF4E (0.44) | EIF4EMAPTTHRBABL1TP53 | |
| SCHEMBL9566872 | 0.77 | EIF4E (0.44) | EIF4EMAPT | |
| SCHEMBL9566874 | 0.77 | EIF4E (0.44) | EIF4EMAPT | |
| SCHEMBL9026777 | 0.77 | EIF4E (0.43) | EIF4EMAPTTHRBABL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544587-B1 | Alpha-methylene-2-vinyl-benzeneacetic acid derivatives, process for their preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1996-05-29 | — | — | EP | claimed |