Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027817 | 0.92 | MAPT (0.43) | TP53MAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL9027940 | 0.91 | MAPT (0.46) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL9029323 | 0.91 | MAPT (0.41) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9034763 | 0.88 | MAPT (0.41) | MAPTSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL9029522 | 0.81 | KDM4E (0.34) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9026598 | 0.80 | EIF4E (0.41) | TP53MAPTGAAKDM4ERECQL | |
| SCHEMBL9027016 | 0.80 | EIF4E (0.41) | TP53MAPTGAAKDM4ERECQL | |
| SCHEMBL9029415 | 0.79 | MAPT (0.45) | TP53MAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL9027553 | 0.74 | PTGDR2 (0.34) | MAPTSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL9401102 | 0.72 | MAPT (0.46) | TP53MAPTSMN1; SMN2GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544587-B1 | Alpha-methylene-2-vinyl-benzeneacetic acid derivatives, process for their preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1996-05-29 | — | — | EP | claimed |
| EP-0544587-A1 | Alpha-methylene-2-vinyl-benzeneacetic acid derivatives, process for their preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1993-06-02 | — | — | EP | claimed |