Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | USP8 | P40818 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028092 | 0.91 | TP53 (0.43) | MAPTTP53MEN1KMT2ARAB9A | |
| SCHEMBL9027940 | 0.90 | MAPT (0.46) | MAPTTHRBMEN1KMT2ARAB9A | |
| SCHEMBL9034763 | 0.87 | MAPT (0.41) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9027817 | 0.84 | MAPT (0.43) | MAPTTP53MEN1KMT2ARAB9A | |
| SCHEMBL9029522 | 0.80 | KDM4E (0.34) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL9401101 | 0.79 | MAPT (0.44) | MAPTTP53THRBMEN1KMT2A | |
| SCHEMBL9026598 | 0.79 | EIF4E (0.41) | MAPTTP53THRBKDM4EPOLB | |
| SCHEMBL9027016 | 0.79 | EIF4E (0.41) | MAPTTP53THRBKDM4EPOLB | |
| SCHEMBL9028920 | 0.73 | RORB (0.33) | MAPTMEN1KMT2AKDM4EDHODH | |
| SCHEMBL9401102 | 0.72 | MAPT (0.46) | MAPTTP53THRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544587-B1 | Alpha-methylene-2-vinyl-benzeneacetic acid derivatives, process for their preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1996-05-29 | — | — | EP | disclosed |
| EP-0544587-A1 | Alpha-methylene-2-vinyl-benzeneacetic acid derivatives, process for their preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1993-06-02 | — | — | EP | disclosed |