Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | GRK2 | P25098 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952643 | 0.80 | L3MBTL1 (0.43) | MAPTSMN1; SMN2GAAL3MBTL1ALDH1A1 | |
| SCHEMBL8952594 | 0.80 | L3MBTL1 (0.43) | MAPTSMN1; SMN2GAAL3MBTL1ALDH1A1 | |
| SCHEMBL9027534 | 0.80 | MAPT (0.46) | MAPTSMN1; SMN2GAAL3MBTL1ALDH1A1 | |
| SCHEMBL7594917 | 0.79 | MAPT (0.44) | MAPTSMN1; SMN2GAAL3MBTL1ALDH1A1 | |
| SCHEMBL9027815 | 0.79 | MAPT (0.44) | MAPTSMN1; SMN2GAAL3MBTL1ALDH1A1 | |
| SCHEMBL8803624 | 0.78 | MAPT (0.43) | MAPTSMN1; SMN2GAAL3MBTL1ALDH1A1 | |
| SCHEMBL9027396 | 0.78 | MAPT (0.43) | MAPTSMN1; SMN2GAAL3MBTL1ALDH1A1 | |
| SCHEMBL9026833 | 0.78 | MAPT (0.43) | MAPTSMN1; SMN2GAAL3MBTL1ALDH1A1 | |
| SCHEMBL9026632 | 0.78 | MAPT (0.43) | MAPTSMN1; SMN2GAAL3MBTL1ALDH1A1 | |
| SCHEMBL8802202 | 0.78 | MAPT (0.43) | MAPTSMN1; SMN2GAAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662834-A4 | NOVEL EPOXIDE-CONTAINING COMPOUNDS. | CELL THERAPEUTICS INC (US) | 1996-04-17 | — | — | EP | disclosed |
| EP-0662834-A1 | NOVEL EPOXIDE-CONTAINING COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1995-07-19 | — | — | EP | disclosed |
| WO-1994006431-A1 | NOVEL EPOXIDE-CONTAINING COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-03-31 | — | — | WO | disclosed |