Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027173 | 0.89 | HTR1A (0.58) | DRD2DRD3HTR1AHTR7HRH1 | |
| SCHEMBL9223276 | 0.85 | HRH3 (0.67) | DRD2DRD3HTR7HTR2AKDM4E | |
| SCHEMBL9027181 | 0.85 | KDM4E (0.43) | DRD2DRD3HTR1AHTR7HRH1 | |
| SCHEMBL9027269 | 0.84 | HRH3 (0.65) | DRD2HTR7HTR2AKDM4EKMT2A | |
| SCHEMBL9026157 | 0.83 | HRH3 (0.64) | DRD2HTR7HTR2AKDM4EKMT2A | |
| SCHEMBL9027094 | 0.83 | HRH3 (0.64) | DRD2HTR7HTR2AKDM4EKMT2A | |
| SCHEMBL9028305 | 0.82 | HRH3 (0.53) | DRD2HTR7HTR2AKDM4EHRH3 | |
| SCHEMBL9026137 | 0.80 | HRH3 (0.43) | HTR7MAPTKMT2ATAAR1HRH3 | |
| SCHEMBL8681907 | 0.74 | DRD2 (0.68) | DRD2DRD3HTR1AHTR7HRH1 | |
| SCHEMBL9027042 | 0.74 | HRH3 (0.56) | DRD2HTR7HTR2AKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537532-B1 | 2,2'-Alkylenediindole derivatives, process for their production, medicines containing them and their use as anti-ulcer agents | NISSHIN FLOUR MILLING CO (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5380723-A | Antiulcer | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5326879-A | Indole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0537532-A1 | 2,2'-Alkylenediindole derivatives, process for their production, medicines containing them and their use as anti-ulcer agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-04-21 | — | — | EP | disclosed |