Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027655 | 0.83 | NR5A1 (0.59) | NR5A1TP53TSHRS1PR1S1PR4 | |
| SCHEMBL1908631 | 0.80 | LTA4H (0.50) | NR5A1TSHR | |
| SCHEMBL6027401 | 0.80 | NR5A1 (0.51) | NR5A1TP53TSHRS1PR1S1PR4 | |
| SCHEMBL2829024 | 0.80 | NR5A1 (0.79) | NR5A1TP53TSHRPLA2G4BNPC1 | |
| SCHEMBL10943900 | 0.80 | NR5A1 (0.79) | NR5A1TP53TSHRPLA2G4BNPC1 | |
| SCHEMBL1573968 | 0.80 | NR5A1 (0.79) | NR5A1TP53TSHRPLA2G4BNPC1 | |
| SCHEMBL28373061 | 0.80 | NR5A1 (0.79) | NR5A1TP53TSHRPLA2G4BNPC1 | |
| SCHEMBL5473083 | 0.80 | NR5A1 (0.79) | NR5A1TP53TSHRPLA2G4BNPC1 | |
| SCHEMBL11095674 | 0.80 | NR5A1 (0.79) | NR5A1TP53TSHRPLA2G4BNPC1 | |
| SCHEMBL8936597 | 0.80 | NR5A1 (0.79) | NR5A1TP53TSHRPLA2G4BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5459142-A | Autoimmune disease, atherosclerosis, antiischemic agents and nephritis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-10-17 | — | — | US | disclosed |
| EP-0511879-B1 | Pyrazine derivatives | OTSUKA PHARMA CO LTD (JP) | 1995-03-22 | — | — | EP | disclosed |
| US-5238938-A | Nephrosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0411150-A1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |