Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.48 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788296 | 0.84 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL19644362 | 0.84 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL9027655 | 0.83 | NR5A1 (0.59) | NR5A1S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL9614864 | 0.82 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL2776407 | 0.82 | ESR1 (0.51) | TP53 | |
| SCHEMBL9027652 | 0.80 | NR5A1 (0.54) | NR5A1S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL9575640 | 0.80 | LMNA (0.39) | — | |
| SCHEMBL10455828 | 0.80 | LMNA (0.39) | TSHR | |
| SCHEMBL3975354 | 0.79 | THRA (0.38) | — | |
| SCHEMBL5560846 | 0.78 | PPARA (0.38) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1631616-A1 | NOVEL SURFACE-ACTIVE POLYSILOXANE PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004108799-A1 | NOVEL SURFACE-ACTIVE POLYSILOXANE PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-12-16 | — | — | WO | disclosed |