Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.35 |
| ▸ | HTR3B | O95264 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14434841 | 1.00 | CHRNA7 (0.40) | CHRNA7F2LMNACHRM2CHRM4 | |
| SCHEMBL25407130 | 0.79 | KMO (0.40) | SLC6A4SLC6A3TSHRSLC6A2 | |
| SCHEMBL7335419 | 0.79 | CTSC (0.42) | CHRNA7CTSC | |
| SCHEMBL7335409 | 0.79 | CTSC (0.42) | CHRNA7CTSC | |
| SCHEMBL7335416 | 0.79 | CTSC (0.42) | CHRNA7CTSC | |
| SCHEMBL7335426 | 0.79 | CTSC (0.42) | CHRNA7CTSC | |
| SCHEMBL2896537 | 0.78 | ALDH1A1 (0.41) | CTSCSLC6A3GAAELANE | |
| SCHEMBL31621126 | 0.78 | ALDH1A1 (0.41) | CTSCSLC6A3GAAELANE | |
| Benzoic Acid SCHEMBL28112972 | 0.76 | DAO (0.47) | TSHR | |
| SCHEMBL8602762 | 0.76 | ALDH1A1 (0.43) | CTSCSLC6A3TSHRGAASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486386-B1 | Novel derivatives of N-benzoylproline, process for their preparation and drugs containing them | ADIR (FR) | 1996-07-17 | — | — | EP | disclosed |
| EP-0486386-A2 | Novel derivatives of N-benzoylproline, process for their preparation and drugs containing them | ADIR ET COMPAGNIE (FR) | 1992-05-20 | — | — | EP | disclosed |