Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 10/20 | 0.41 |
| ▸ | GABRP | O00591 | 9/20 | 0.41 |
| ▸ | GABRD | O14764 | 9/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 9/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 9/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 9/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 9/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 9/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 9/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 9/20 | 0.41 |
| ▸ | GABRE | P78334 | 9/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 9/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 9/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 9/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 9/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8822818 | 0.73 | GABRA2 (0.42) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9119928 | 0.73 | GABRA2 (0.38) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9026541 | 0.71 | GABRB3 (0.48) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9028426 | 0.71 | GABRB3 (0.48) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8822792 | 0.71 | GABRB3 (0.47) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8823000 | 0.70 | GABRB3 (0.39) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9167863 | 0.70 | GABRB3 (0.53) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9118225 | 0.69 | GABRA2 (0.36) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8822906 | 0.69 | GABRA2 (0.38) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8822796 | 0.69 | GABRB3 (0.41) | GABRB3GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506260-A | INSECTICIDES, ACARICIDES, NEMATOCIDES | RHONE-POULENC AG COMPANY (US) | 1996-04-09 | — | — | US | disclosed |
| US-5187185-A | Pesticidal 1-arylpyrroles | RHONE-POULENC AG COMPANY (US) | 1993-02-16 | — | — | US | disclosed |