Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44641 | 0.89 | POLB (0.48) | POLBKMT2ATSHRKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL1131672 | 0.87 | POLB (0.46) | POLBKMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL5280013 | 0.84 | POLB (0.93) | POLBKMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL29905605 | 0.84 | POLB (0.93) | POLBKMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL1546827 | 0.81 | POLB (0.87) | POLBKMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL3176249 | 0.75 | KDM4E (1.00) | POLBKMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL22095572 | 0.75 | POLB (0.36) | POLBKMT2ATSHRKDM4ESMN1; SMN2 | |
| SCHEMBL5314300 | 0.74 | KMT2A (0.81) | POLBKMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL16439724 | 0.72 | KDM4E (0.95) | POLBKMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL11412844 | 0.70 | L3MBTL1 (0.38) | TSHRALDH1A1SMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695292-A1 | HERBICIDAL (4-SUBSTITUTED PYRIDYL)-3-CARBINOLS | ZENECA LIMITED (GB) | 1996-02-07 | — | — | EP | claimed |
| WO-1994024106-A1 | HERBICIDAL (4-SUBSTITUTED PYRIDYL)-3-CARBINOLS | ZENECA LIMITED (GB) | 1994-10-27 | — | — | WO | claimed |