Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.61 |
| ▸ | EBP | Q15125 | 2/20 | 0.61 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | EBPL | Q9BY08 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27337543 | 0.82 | SIGMAR1 (0.64) | SIGMAR1EBPTMEM97HSP90AA1DHCR7 | |
| SCHEMBL6625725 | 0.81 | SIGMAR1 (0.63) | SIGMAR1EBPTMEM97ADRA1DADRA1A | |
| SCHEMBL8075010 | 0.81 | SIGMAR1 (0.89) | SIGMAR1EBPTMEM97EBPL | |
| SCHEMBL9397288 | 0.81 | SIGMAR1 (0.63) | SIGMAR1EBPTMEM97HSP90AA1DHCR7 | |
| SCHEMBL3714297 | 0.80 | SIGMAR1 (0.75) | SIGMAR1ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL1332052 | 0.79 | SIGMAR1 (0.61) | SIGMAR1EBPTMEM97ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL8088180 | 0.79 | SIGMAR1 (0.87) | SIGMAR1EBPTMEM97EBPL | |
| SCHEMBL9829278 | 0.79 | KMT2A (0.58) | SIGMAR1HTTALDH1A1MAPK1 | |
| SCHEMBL27877058 | 0.79 | SIGMAR1 (0.64) | SIGMAR1EBPTMEM97EBPLMAPK1 | |
| SCHEMBL4285168 | 0.79 | HSP90AA1 (0.61) | SIGMAR1EBPTMEM97HSP90AA1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700385-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027967-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1994-12-08 | — | — | WO | disclosed |