Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.63 |
| ▸ | EBP | Q15125 | 2/20 | 0.63 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.63 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.55 |
| ▸ | EBPL | Q9BY08 | 1/20 | 0.54 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397184 | 0.94 | SIGMAR1 (0.57) | SIGMAR1EBPTMEM97ADRA1DADRA1A | |
| SCHEMBL9432931 | 0.89 | EBP (0.61) | SIGMAR1EBPTMEM97EBPL | |
| SCHEMBL2092284 | 0.84 | KMT2A (0.54) | SIGMAR1 | |
| SCHEMBL8310274 | 0.83 | KDM4E (0.49) | SIGMAR1EBPTMEM97 | |
| SCHEMBL27337543 | 0.83 | SIGMAR1 (0.64) | SIGMAR1EBPTMEM97ADRA1DADRA1A | |
| SCHEMBL8075010 | 0.82 | SIGMAR1 (0.89) | SIGMAR1EBPTMEM97EBPL | |
| SCHEMBL6625725 | 0.82 | SIGMAR1 (0.63) | SIGMAR1EBPTMEM97ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL8088180 | 0.81 | SIGMAR1 (0.87) | SIGMAR1EBPTMEM97EBPL | |
| Hydrochloric Acid SCHEMBL1332052 | 0.81 | SIGMAR1 (0.61) | SIGMAR1EBPTMEM97ADRA1DADRA1A | |
| SCHEMBL9028169 | 0.81 | SIGMAR1 (0.61) | SIGMAR1EBPTMEM97ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358949-A | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| US-5340811-A | Bronchodilator agent | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0471841-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-02-26 | — | — | EP | disclosed |
| EP-0236140-A2 | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |