Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027973 | 0.90 | IDO1 (0.52) | RAB9ANPC1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL6961677 | 0.87 | MEN1 (0.56) | RAB9ASMN1; SMN2POLBHTTTSHR | |
| SCHEMBL6960067 | 0.87 | MEN1 (0.56) | RAB9ASMN1; SMN2POLBHTTTSHR | |
| SCHEMBL6972274 | 0.82 | HDAC6 (0.55) | POLBTSHRL3MBTL1HDAC2HDAC8 | |
| SCHEMBL6973879 | 0.81 | HDAC6 (0.54) | RAB9APOLBTSHRLMNAHPGD | |
| SCHEMBL9023637 | 0.80 | ALDH1A1 (0.46) | RAB9ANPC1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL9078769 | 0.80 | CYP19A1 (0.36) | RAB9ANPC1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL6973817 | 0.79 | POLB (0.53) | RAB9ANPC1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL6968562 | 0.79 | POLB (0.53) | RAB9ANPC1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL17548986 | 0.78 | HDAC2 (0.47) | RAB9ANPC1SMN1; SMN2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |
| EP-0729459-A1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995014007-A1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 1995-05-26 | — | — | WO | disclosed |