Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027127 | 0.90 | MAPT (0.41) | ALDH1A1L3MBTL1CYP2C9CYP2C19NPSR1 | |
| SCHEMBL6961218 | 0.87 | KMT2A (0.50) | ALDH1A1L3MBTL1CYP2C9CYP2C19NPSR1 | |
| SCHEMBL6960634 | 0.87 | KMT2A (0.50) | ALDH1A1L3MBTL1CYP2C9CYP2C19NPSR1 | |
| SCHEMBL9080811 | 0.84 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1CYP2C9CYP2C19NPSR1 | |
| SCHEMBL6967651 | 0.82 | KMT2A (0.56) | ALDH1A1L3MBTL1CYP2C9CYP2C19NPSR1 | |
| SCHEMBL9028085 | 0.81 | KMT2A (0.55) | ALDH1A1L3MBTL1KMT2AMAPTGAA | |
| SCHEMBL10511862 | 0.81 | LOXL2 (0.38) | KMT2ARAB9ANPC1MRGPRX4SMN1; SMN2 | |
| SCHEMBL9028240 | 0.80 | RAB9A (0.55) | ALDH1A1L3MBTL1CYP2C9CYP2C19NPSR1 | |
| SCHEMBL9033928 | 0.80 | SMN1; SMN2 (0.38) | L3MBTL1KMT2ARAB9ANPC1MRGPRX4 | |
| SCHEMBL6964272 | 0.79 | KMT2A (0.49) | ALDH1A1L3MBTL1CYP2C9CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |
| EP-0729459-A1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995014007-A1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 1995-05-26 | — | — | WO | disclosed |