Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028262 | 1.00 | ITGB3 (0.35) | ITGB3ITGA2BKDM4EALDH1A1CA12 | |
| SCHEMBL27529645 | 0.89 | ITGB3 (0.35) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL27351399 | 0.86 | ITGB3 (0.31) | ITGB3ITGA2BKDM4EALDH1A1PTPN1 | |
| SCHEMBL7417390 | 0.86 | ITGB3 (0.31) | ITGB3ITGA2BKDM4EALDH1A1PTPN1 | |
| SCHEMBL9042071 | 0.85 | POLB (0.41) | ALDH1A1PTPN1 | |
| SCHEMBL27398646 | 0.84 | ITGB3 (0.36) | ITGB3ITGA2BKDM4EALDH1A1 | |
| SCHEMBL9029392 | 0.84 | OPRM1 (0.35) | ITGB3ITGA2BKDM4EALDH1A1PTPN1 | |
| SCHEMBL7422020 | 0.83 | ITGB3 (0.49) | ITGB3ITGA2BKDM4EALDH1A1CA12 | |
| SCHEMBL9028218 | 0.83 | ITGB3 (0.40) | ITGB3ITGA2B | |
| SCHEMBL8122271 | 0.83 | ITGB3 (0.36) | ITGB3ITGA2BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-01-17 | — | — | EP | claimed |