Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028029 | 0.88 | ECE1 (0.34) | ECE1CHRM1CYP19A1FAAHCA1 | |
| SCHEMBL9027684 | 0.86 | ECE1 (0.35) | ECE1CHRM1CYP19A1FAAHCA1 | |
| SCHEMBL9028139 | 0.81 | ECE1 (0.34) | ECE1CHRM1CYP19A1CA1CA2 | |
| SCHEMBL9028304 | 0.80 | ECE1 (0.36) | ECE1CHRM1CYP19A1 | |
| SCHEMBL9028036 | 0.80 | ECE1 (0.37) | ECE1CHRM1CYP19A1 | |
| SCHEMBL8833609 | 0.79 | ECE1 (0.38) | ECE1CHRM1CYP19A1FAAH | |
| SCHEMBL9059569 | 0.79 | ECE1 (0.36) | ECE1CHRM1CYP19A1 | |
| SCHEMBL8833492 | 0.78 | ECE1 (0.37) | ECE1CHRM1CYP19A1FAAH | |
| SCHEMBL9215980 | 0.78 | ECE1 (0.37) | ECE1CHRM1CYP19A1FAAH | |
| SCHEMBL9027724 | 0.78 | ECE1 (0.37) | ECE1CHRM1CYP19A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722447-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995010520-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-20 | — | — | WO | disclosed |