Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GLS | O94925 | 2/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833492 | 1.00 | ECE1 (0.37) | ECE1CHRM1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8833609 | 0.86 | ECE1 (0.38) | ECE1CHRM1MEN1KMT2AKDM4E | |
| SCHEMBL9027523 | 0.84 | ECE1 (0.37) | ECE1CHRM1FAAHMGLL | |
| SCHEMBL9027518 | 0.84 | ECE1 (0.37) | ECE1CHRM1FAAHMGLL | |
| SCHEMBL8832597 | 0.84 | ECE1 (0.36) | ECE1CHRM1MEN1KMT2ACYP19A1 | |
| SCHEMBL8833600 | 0.84 | LMNA (0.38) | ECE1CHRM1CHRNB2CHRNA4KMT2A | |
| SCHEMBL9027724 | 0.83 | ECE1 (0.37) | ECE1CHRM1MEN1KMT2ACYP19A1 | |
| SCHEMBL9027719 | 0.83 | ECE1 (0.37) | ECE1CHRM1MEN1KMT2ACYP19A1 | |
| SCHEMBL8834048 | 0.83 | ECE1 (0.38) | ECE1CHRM1KMT2ACYP19A1FAAH | |
| SCHEMBL9027722 | 0.83 | ECE1 (0.38) | ECE1CHRM1KMT2ACYP19A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636133-A1 | SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |