Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833600 | 0.90 | LMNA (0.38) | ECE1CHRM1ABCB1KMT2A | |
| SCHEMBL9027719 | 0.88 | ECE1 (0.37) | ECE1CHRM1TACR1ELANEABCB1 | |
| SCHEMBL9027724 | 0.88 | ECE1 (0.37) | ECE1CHRM1TACR1ELANEABCB1 | |
| SCHEMBL9027798 | 0.87 | ECE1 (0.36) | ECE1CHRM1FAAHMGLLMEN1 | |
| SCHEMBL9026112 | 0.87 | ECE1 (0.36) | ECE1CHRM1FAAHMGLLMEN1 | |
| SCHEMBL8833492 | 0.86 | ECE1 (0.37) | ECE1CHRM1FAAHMGLLL3MBTL1 | |
| SCHEMBL9215980 | 0.86 | ECE1 (0.37) | ECE1CHRM1FAAHMGLLL3MBTL1 | |
| SCHEMBL9025780 | 0.86 | ECE1 (0.37) | ECE1CHRM1ABCB1FAAHMGLL | |
| SCHEMBL9025782 | 0.86 | ECE1 (0.37) | ECE1CHRM1ABCB1FAAHMGLL | |
| SCHEMBL8832778 | 0.85 | ECE1 (0.36) | ECE1CHRM1ELANEABCB1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608056-A | Substituted 3-pyrrolidinylthio-carbapenems as antimicrobial agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |