Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropylbenzene SCHEMBL6568803 | 0.86 | GAA (0.48) | GAAL3MBTL1IDO1SIGMAR1EPHX1 | |
| SCHEMBL28855188 | 0.82 | SIGMAR1 (0.43) | GAAL3MBTL1IDO1SIGMAR1 | |
| SCHEMBL4916236 | 0.80 | DPP4 (0.58) | SIGMAR1LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL5559781 | 0.80 | DPP4 (0.58) | SIGMAR1LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL29380238 | 0.80 | — | — | |
| SCHEMBL24932018 | 0.80 | DPP4 (0.58) | SIGMAR1LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL42393 | 0.80 | — | — | |
| SCHEMBL42904 | 0.80 | — | — | |
| SCHEMBL5565016 | 0.80 | DPP4 (0.58) | SIGMAR1LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL830 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535250-B1 | NOVEL COMPOUNDS AND USE THEREOF AS MEDICINE | TSUMURA & CO (JP) | 1996-06-19 | — | — | EP | disclosed |
| EP-0705817-A1 | New cannamide derivatives and their use as allergy inhibitors | TSUMURA & CO. (JP) | 1996-04-10 | — | — | EP | disclosed |
| US-5344845-A | Methyl 4(4-acetoxy-3-methoxycinnamanide and salts as an immunosuppressive drug for allergic reactions | TSUMURA & CO. (JP) | 1994-09-06 | — | — | US | disclosed |
| EP-0535250-A1 | NOVEL COMPOUNDS AND USE THEREOF AS MEDICINE | TSUMURA & CO. (JP) | 1993-04-07 | — | — | EP | disclosed |