Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 19/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 19/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 19/20 | 0.45 |
| ▸ | GABRP | O00591 | 17/20 | 0.45 |
| ▸ | GABRD | O14764 | 17/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 17/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 17/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 17/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 17/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 17/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 17/20 | 0.45 |
| ▸ | GABRE | P78334 | 17/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 17/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 17/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 17/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 17/20 | 0.45 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027896 | 0.85 | GABRB3 (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9026541 | 0.80 | GABRB3 (0.48) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL8822792 | 0.79 | GABRB3 (0.47) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9354067 | 0.78 | GABRP (0.50) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9028426 | 0.77 | GABRB3 (0.48) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL8822800 | 0.76 | GABRB3 (0.45) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL8822796 | 0.75 | GABRB3 (0.41) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9028583 | 0.72 | GABRB3 (0.43) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9028676 | 0.72 | GABRP (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9353720 | 0.72 | GABRP (0.53) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460940-A1 | Pesticidal 1-arylpyrroles | RHONE-POULENC AGROCHIMIE (FR) | 1991-12-11 | — | — | EP | claimed |
| US-5506260-A | INSECTICIDES, ACARICIDES, NEMATOCIDES | RHONE-POULENC AG COMPANY (US) | 1996-04-09 | — | — | US | disclosed |
| US-5187185-A | Pesticidal 1-arylpyrroles | RHONE-POULENC AG COMPANY (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0460940-A1 | Pesticidal 1-arylpyrroles | RHONE-POULENC AGROCHIMIE (FR) | 1991-12-11 | — | — | EP | disclosed |