Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL205044 | 0.81 | KDM4E (0.50) | GAAALDH1A1HTTKDM4EPOLB | |
| SCHEMBL6945356 | 0.80 | GAA (0.50) | GAAALDH1A1HTTKDM4EPOLB | |
| SCHEMBL24379065 | 0.80 | GAA (0.54) | GAAALDH1A1HTTKDM4EPOLB | |
| SCHEMBL644055 | 0.80 | KDM4E (0.57) | GAAALDH1A1HTTKDM4EPOLB | |
| SCHEMBL31347582 | 0.80 | GAA (0.50) | GAAALDH1A1HTTKDM4EPOLB | |
| SCHEMBL3970999 | 0.79 | GAA (0.50) | GAAALDH1A1HTTKDM4EPOLB | |
| SCHEMBL11156433 | 0.79 | KDM4E (0.60) | GAAALDH1A1HTTKDM4EPOLB | |
| SCHEMBL204076 | 0.79 | GAA (0.48) | GAAALDH1A1HTTKDM4EPOLB | |
| SCHEMBL1822622 | 0.79 | GAA (0.48) | GAAALDH1A1HTTKDM4EPOLB | |
| SCHEMBL8750267 | 0.79 | GAA (0.48) | GAAALDH1A1HTTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012042482-A1 | PROCESS FOR THE SYNTHESIS OF FUNICONE ANALOGUES | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2012-04-05 | — | — | WO | disclosed |