SCHEMBL205044

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL205045	0.93	LMNA (0.49)	KDM4EGAAALDH1A1HTTCYP1A2
	SCHEMBL6945356	0.83	GAA (0.50)	KDM4EGAAALDH1A1HTTCYP1A2
	SCHEMBL31347582	0.83	GAA (0.50)	KDM4EGAAALDH1A1HTTCYP1A2
	SCHEMBL24379065	0.83	GAA (0.54)	KDM4EGAAALDH1A1HTTCYP1A2
	SCHEMBL644055	0.83	KDM4E (0.57)	KDM4EGAAALDH1A1HTTCYP1A2
	SCHEMBL3970999	0.81	GAA (0.50)	KDM4EGAAALDH1A1HTTCYP1A2
	SCHEMBL204076	0.81	GAA (0.48)	KDM4EGAAALDH1A1HTTCYP1A2
	SCHEMBL1822622	0.81	GAA (0.48)	KDM4EGAAALDH1A1HTTCYP1A2
	SCHEMBL902865	0.81	GAA (0.51)	KDM4EGAAALDH1A1HTTCYP1A2
	SCHEMBL11156433	0.81	KDM4E (0.60)	KDM4EGAAALDH1A1HTTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.