Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 7/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027567 | 0.98 | MEN1 (0.43) | EPHX2MEN1KMT2AOPRD1OPRK1 | |
| SCHEMBL8884615 | 0.95 | TACR1 (0.45) | EPHX2MEN1KMT2AOPRD1OPRK1 | |
| SCHEMBL9026960 | 0.90 | TACR2 (0.42) | TACR1USP2GLACYP3A4CYP2D6 | |
| SCHEMBL9029048 | 0.90 | TACR2 (0.42) | TACR1USP2GLACYP3A4CYP2D6 | |
| SCHEMBL9027233 | 0.89 | CYP3A4 (0.40) | EPHX2MEN1KMT2AOPRD1OPRK1 | |
| SCHEMBL9027166 | 0.88 | CYP3A4 (0.40) | EPHX2MEN1KMT2AOPRD1OPRK1 | |
| SCHEMBL9027646 | 0.88 | TACR2 (0.42) | MEN1KMT2ATACR1 | |
| SCHEMBL9028242 | 0.88 | CYP3A4 (0.40) | EPHX2MEN1KMT2AOPRD1OPRK1 | |
| SCHEMBL9027505 | 0.88 | TACR2 (0.42) | MEN1KMT2ATACR1 | |
| SCHEMBL9026988 | 0.87 | CYP3A4 (0.41) | EPHX2MEN1KMT2AOPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714891-A1 | Heterocyclic tachykinin receptor antagonists | ELI LILLY AND COMPANY (US) | 1996-06-05 | — | — | EP | disclosed |