Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.45 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1425605 | 0.92 | MAPT (0.61) | MAPTALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL4114732 | 0.80 | ALDH1A1 (0.51) | MAPTALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL12811588 | 0.80 | NPC1 (0.59) | MAPTALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL14527733 | 0.79 | ALDH1A1 (0.45) | MAPTALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL1425588 | 0.79 | PPARA (0.49) | MAPTALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL18614346 | 0.78 | MAPT (0.54) | MAPTALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL1426050 | 0.78 | MAPT (0.52) | MAPTALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL16370488 | 0.78 | ALDH1A1 (0.59) | MAPTALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL1425593 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HSP90AA1MEN1KMT2AL3MBTL1 | |
| SCHEMBL4101439 | 0.76 | PPARD (0.44) | MAPTALDH1A1TP53HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726261-A1 | Herbidical 1,2,4 thiadiazoles | American Cyanamid Company (US) | 1996-08-14 | — | — | EP | disclosed |