Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.66 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.66 |
| ▸ | FPR2 | P25090 | 12/20 | 0.41 |
| ▸ | FPR1 | P21462 | 8/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448817 | 0.95 | ITGB3 (0.73) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7411805 | 0.95 | ITGB3 (0.73) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL9095786 | 0.89 | ITGB3 (0.71) | ITGB3ITGA2BFPR2FPR1 | |
| Trifluoroacetic Acid SCHEMBL9029015 | 0.87 | ITGB3 (0.64) | ITGB3ITGA2BFPR2FPR1 | |
| Trifluoroacetic Acid SCHEMBL7448806 | 0.83 | ITGB3 (0.68) | ITGB3ITGA2BFPR2FPR1 | |
| Trifluoroacetic Acid SCHEMBL7411796 | 0.83 | ITGB3 (0.68) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7418344 | 0.83 | ITGB3 (0.80) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7422015 | 0.82 | ITGB3 (0.56) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| Acetic Acid SCHEMBL9095776 | 0.82 | ITGB3 (0.69) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7451885 | 0.82 | ITGB3 (0.84) | ITGB3ITGA2BFPR2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-01-17 | — | — | EP | claimed |