Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028938 | 1.00 | ALDH1A1 (0.47) | ALDH1A1POLBRECQLTSHRGNAI3 | |
| SCHEMBL13744511 | 0.94 | ALDH1A1 (0.49) | ALDH1A1POLBRECQLTSHRGNAI3 | |
| SCHEMBL9028752 | 0.86 | ALDH1A1 (0.56) | ALDH1A1POLBRECQLTSHRSMN1; SMN2 | |
| SCHEMBL9030143 | 0.86 | ALDH1A1 (0.56) | ALDH1A1POLBRECQLTSHRSMN1; SMN2 | |
| SCHEMBL9028760 | 0.86 | ALDH1A1 (0.56) | ALDH1A1POLBRECQLTSHRSMN1; SMN2 | |
| SCHEMBL22462391 | 0.83 | GNAI3 (0.48) | ALDH1A1POLBRECQLTSHRGNAI3 | |
| SCHEMBL8851102 | 0.79 | GNAI3 (0.36) | ALDH1A1TSHRGNAI3GNAO1GNAI1 | |
| SCHEMBL18977791 | 0.78 | GNAI3 (0.58) | GNAI3GNAO1GNAI1S1PR4S1PR1 | |
| SCHEMBL6657954 | 0.77 | TDP1 (0.39) | ALDH1A1POLBRECQLTSHRGNAI3 | |
| SCHEMBL6013549 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535250-B1 | NOVEL COMPOUNDS AND USE THEREOF AS MEDICINE | TSUMURA & CO (JP) | 1996-06-19 | — | — | EP | disclosed |
| EP-0705817-A1 | New cannamide derivatives and their use as allergy inhibitors | TSUMURA & CO. (JP) | 1996-04-10 | — | — | EP | disclosed |
| US-5344845-A | Methyl 4(4-acetoxy-3-methoxycinnamanide and salts as an immunosuppressive drug for allergic reactions | TSUMURA & CO. (JP) | 1994-09-06 | — | — | US | disclosed |
| EP-0535250-A1 | NOVEL COMPOUNDS AND USE THEREOF AS MEDICINE | TSUMURA & CO. (JP) | 1993-04-07 | — | — | EP | disclosed |