Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.30 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029476 | 1.00 | ITGB3 (0.36) | ITGB3ITGA2BAVPR2AVPR1A | |
| SCHEMBL27366172 | 0.90 | ITGB3 (0.33) | ITGB3ITGA2B | |
| SCHEMBL7424236 | 0.87 | ITGB3 (0.36) | ITGB3ITGA2BAVPR2AVPR1A | |
| SCHEMBL7424245 | 0.87 | ITGB3 (0.36) | ITGB3ITGA2BAVPR2AVPR1A | |
| SCHEMBL9029449 | 0.85 | F9 (0.40) | ITGB3ITGA2B | |
| SCHEMBL8110671 | 0.85 | F9 (0.40) | ITGB3ITGA2B | |
| SCHEMBL7419108 | 0.84 | ITGB3 (0.35) | ITGB3ITGA2BAVPR2AVPR1A | |
| SCHEMBL7421385 | 0.83 | ITGB3 (0.44) | ITGB3ITGA2B | |
| SCHEMBL7417001 | 0.83 | ITGB3 (0.44) | ITGB3ITGA2B | |
| SCHEMBL8108831 | 0.83 | ITGB3 (0.35) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1054842-C | Platelet aggregation inhibitors | SEARLE & CO (US) | 2000-07-26 | — | — | CN | claimed |
| CN-1124957-A | 1-amidinophenyl-pyrrolidones piperidinones azetinones as platelet aggregation inhibitors | SEARLE & CO (US) | 1996-06-19 | — | — | CN | claimed |
| EP-0691953-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-01-17 | — | — | EP | claimed |