Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 10/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029533 | 1.00 | SIGMAR1 (0.47) | SIGMAR1PYGLTRPM8CCR2GAA | |
| SCHEMBL9029549 | 1.00 | SIGMAR1 (0.47) | SIGMAR1PYGLTRPM8CCR2GAA | |
| Hydrochloric Acid SCHEMBL9030134 | 0.99 | SIGMAR1 (0.47) | SIGMAR1PYGLTRPM8CCR2GAA | |
| Hydrochloric Acid SCHEMBL9030125 | 0.99 | SIGMAR1 (0.47) | SIGMAR1PYGLTRPM8CCR2GAA | |
| Hydrochloric Acid SCHEMBL9030127 | 0.99 | SIGMAR1 (0.47) | SIGMAR1PYGLTRPM8CCR2GAA | |
| SCHEMBL9029270 | 0.86 | KLF5 (0.46) | SIGMAR1TRPM8MAPT | |
| SCHEMBL9029259 | 0.86 | KLF5 (0.46) | SIGMAR1TRPM8MAPT | |
| SCHEMBL9029263 | 0.86 | KLF5 (0.46) | SIGMAR1TRPM8MAPT | |
| Hydrochloric Acid SCHEMBL9030590 | 0.85 | KLF5 (0.46) | TRPM8MAPT | |
| Hydrochloric Acid SCHEMBL9030592 | 0.85 | KLF5 (0.46) | TRPM8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535250-B1 | NOVEL COMPOUNDS AND USE THEREOF AS MEDICINE | TSUMURA & CO (JP) | 1996-06-19 | — | — | EP | disclosed |
| EP-0705817-A1 | New cannamide derivatives and their use as allergy inhibitors | TSUMURA & CO. (JP) | 1996-04-10 | — | — | EP | disclosed |
| US-5344845-A | Methyl 4(4-acetoxy-3-methoxycinnamanide and salts as an immunosuppressive drug for allergic reactions | TSUMURA & CO. (JP) | 1994-09-06 | — | — | US | disclosed |
| EP-0535250-A1 | NOVEL COMPOUNDS AND USE THEREOF AS MEDICINE | TSUMURA & CO. (JP) | 1993-04-07 | — | — | EP | disclosed |