SCHEMBL9029618

SCHEMBL9029618

COc1cc(CCC(=O)NC2CCC(C)CC2)ccc1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.59
OR51E2 Q9H255 1/20 0.59
GAA P10253 1/20 0.53
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
BCHE P06276 1/20 0.50
ACHE P22303 1/20 0.50
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C8 P10632 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2B6 P20813 1/20 0.49
CYP2C19 P33261 1/20 0.49
TAS1R3 Q7RTX0 1/20 0.49
TAS1R1 Q7RTX1 1/20 0.49
TAS1R2 Q8TE23 1/20 0.49
TRPV1 Q8NER1 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
MTNR1A P48039 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9029611 1.00 ALOX5 (0.59) ALOX5OR51E2GAANPC1RAB9A
SCHEMBL9029416 0.92 TRPV1 (0.53) ALOX5OR51E2GAANPC1RAB9A
SCHEMBL9029421 0.92 TRPV1 (0.53) ALOX5OR51E2GAANPC1RAB9A
SCHEMBL9425620 0.89 ALOX5 (0.60) ALOX5OR51E2CYP1A2CYP3A4CYP2C9
SCHEMBL2969801 0.89 GAA (0.60) ALOX5OR51E2GAANPC1RAB9A
SCHEMBL9028338 0.89 GAA (0.60) ALOX5OR51E2GAANPC1RAB9A
SCHEMBL13202133 0.89 GAA (0.60) ALOX5OR51E2GAANPC1RAB9A
SCHEMBL9029800 0.83 NPC1 (0.51) GAANPC1RAB9AMEN1KMT2A
SCHEMBL9029791 0.83 NPC1 (0.51) GAANPC1RAB9AMEN1KMT2A
SCHEMBL9030563 0.82 NPC1 (0.50) GAANPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0535250-B1 NOVEL COMPOUNDS AND USE THEREOF AS MEDICINE TSUMURA & CO (JP) 1996-06-19 EP disclosed
EP-0705817-A1 New cannamide derivatives and their use as allergy inhibitors TSUMURA & CO. (JP) 1996-04-10 EP disclosed
US-5344845-A Methyl 4(4-acetoxy-3-methoxycinnamanide and salts as an immunosuppressive drug for allergic reactions TSUMURA & CO. (JP) 1994-09-06 US disclosed
EP-0535250-A1 NOVEL COMPOUNDS AND USE THEREOF AS MEDICINE TSUMURA & CO. (JP) 1993-04-07 EP disclosed