Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 9/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.56 |
| ▸ | PGR | P06401 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029850 | 1.00 | NR3C2 (0.56) | NR3C2NR3C1PGRMEN1KMT2A | |
| SCHEMBL20804552 | 0.83 | MEN1 (0.55) | NR3C2NR3C1PGRMEN1KMT2A | |
| SCHEMBL20804963 | 0.80 | NR3C2 (0.52) | NR3C2NR3C1PGRMEN1KMT2A | |
| SCHEMBL13767851 | 0.79 | MEN1 (0.64) | MEN1KMT2ANOTUMBRD4KIF11 | |
| SCHEMBL20804842 | 0.79 | MEN1 (0.42) | NR3C2NR3C1PGRMEN1KMT2A | |
| SCHEMBL25883473 | 0.77 | NR3C1 (0.45) | NR3C2NR3C1PGRMEN1KMT2A | |
| SCHEMBL19418286 | 0.76 | NR3C2 (0.44) | NR3C2NR3C1PGRMEN1KMT2A | |
| SCHEMBL17363701 | 0.75 | NR3C2 (0.44) | NR3C2NR3C1PGRMEN1KMT2A | |
| SCHEMBL20804531 | 0.75 | KDM4E (0.49) | NR3C2NR3C1PGRMEN1KMT2A | |
| SCHEMBL20804663 | 0.75 | NR3C1 (0.45) | NR3C2NR3C1PGRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019050988-A1 | VASOPRESSIN RECEPTOR ANTAGONISTS AND PRODUCTS AND METHODS RELATED THERETO | BLACKTHORN THERAPEUTICS, INC. (US) | 2019-03-14 | — | — | WO | disclosed |
| CN-1140174-A | Piperidine derivatives, process for preparation thereof and application thereof in therapeutics | SYNTHELABO (FR) | 1997-01-15 | — | — | CN | disclosed |
| EP-0732334-A1 | Piperidine derivatives, process for their preparation and their therapeutic application | SYNTHELABO (FR) | 1996-09-18 | — | — | EP | disclosed |