SCHEMBL9030258

SCHEMBL9030258

CC(C)(COCc1cccc(Oc2ccccc2)c1)c1ccc(Cl)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.45
PPARA Q07869 1/20 0.45
ALDH1A1 P00352 3/20 0.44
NPC1 O15118 1/20 0.42
POLB P06746 1/20 0.42
CYP2C9 P11712 1/20 0.42
RAB9A P51151 1/20 0.42
DAGLA Q9Y4D2 1/20 0.41
LMNA P02545 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
ADRA2A P08913 1/20 0.41
CNR1 P21554 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HTT P42858 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
GAA P10253 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
CETP P11597 1/20 0.39
KDM4E B2RXH2 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10851466 0.92 ALDH1A1 (0.41) PPARGPPARAALDH1A1NPC1POLB
SCHEMBL10859391 0.92 NPC1 (0.49) ALDH1A1NPC1POLBCYP2C9RAB9A
SCHEMBL10855015 0.91 ALDH1A1 (0.44) PPARGPPARAALDH1A1NPC1POLB
SCHEMBL10857765 0.91 HTT (0.46) PPARGPPARAALDH1A1NPC1POLB
SCHEMBL10532258 0.90 NPC1 (0.44) ALDH1A1NPC1POLBCYP2C9RAB9A
SCHEMBL10854414 0.90 ALDH1A1 (0.44) PPARGPPARAALDH1A1NPC1POLB
SCHEMBL10854155 0.90 ALDH1A1 (0.44) PPARGPPARAALDH1A1NPC1POLB
SCHEMBL10849595 0.90 HTT (0.42) PPARGPPARAALDH1A1NPC1POLB
SCHEMBL10851699 0.90 TDP1 (0.41) PPARGPPARAALDH1A1NPC1POLB
SCHEMBL9558481 0.89 FAAH (0.45) ALDH1A1NPC1POLBCYP2C9RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57056438-A None JP disclosed
EP-0490323-B1 Imidazolidine derivatives, preparation thereof, insecticides containing same as an effective ingredient and intermediates therefor MITSUI TOATSU CHEMICALS (JP) 1996-05-01 EP disclosed
EP-0455000-B1 Dialkoxymethylimidazolidine derivatives, preparation thereof, insecticides containing same as an effective ingredient and intermediates therefor MITSUI TOATSU CHEMICALS (JP) 1996-01-31 EP disclosed
EP-0547557-B1 N-vinylimidazolidine derivatives, preparation thereof, insecticides containing same as an effective ingredient and intermediates thereof MITSUI TOATSU CHEMICALS (JP) 1994-07-27 EP disclosed
US-5310920-A N-vinylimidazolidine derivatives insecticides containing same as an effective ingredient MITSUI TOATSU CHEMICALS, INC. (JP) 1994-05-10 US disclosed
US-5264584-A Dialkoxymethylimidazolidine derivatives MITSUI TOATSU CHEMICALS, INC. (JP) 1993-11-23 US disclosed
EP-0547557-A1 N-vinylimidazolidine derivatives, preparation thereof, insecticides containing same as an effective ingredient and intermediates thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-06-23 EP disclosed
US-5219868-A Insecticides MITSUI TOATSU CHEMICALS, INC. (JP) 1993-06-15 US disclosed
EP-0257415-B1 INSECTICIDAL RESIN COATING FILM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
US-5192778-A DIALKOXYMETHYLIMIDAZOLIDINE DERIVATIVES, PREPARATION THEREOF, INSECTICIDES CONTAINING SAME AS AN EFFECTIVE INGREDIENT AND INTERMEDIATES THEREFOR MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-09 US disclosed
US-4997650-A (Meth)acrylonitrile polymer MITSUI TOATSU CHEMICALS, INC. (JP) 1991-03-05 US disclosed
US-4818525-A LONG-LASTING; ACRYLONITRILE COPOLYMER MITSUI TOATSU CHEMICALS, INC. (JP) 1989-04-04 US disclosed
US-4814340-A 1,4-diaryl alkane derivatives having insecticidal and acaricidal activity MITSUI TOATSU CHEMICALS, INC. (JP) 1989-03-21 US disclosed
US-4782094-A Difluorobromomethoxyphenyl derivative and miticide comprising said derivative as active ingredient MITSUI TOATSU CHEMICALS, INC. (JP) 1988-11-01 US disclosed
EP-0257415-A1 Insecticidal resin coating film MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-03-02 EP disclosed
US-4661501-A Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity MITSUI TOATSU CHEMICALS, INC. (JP) 1987-04-28 US disclosed
EP-0207728-A2 Novel pyrazoline compounds, process for production thereof, and insecticides containing them as active ingredients MITSUI TOATSU CHEMICALS, Inc. (JP) 1987-01-07 EP disclosed
US-4570005-A REACTING THE ARYL PROPYL CHLORIDE WITH THE CORRESPONDING ARYL ALCOHOL OR ARYL MERCAPTAN MITSUITOATSU CHEMICALS INC. (JP) 1986-02-11 US disclosed
US-4397864-A LOW TOXICITY MITSUITOATSU CHEMICALS INC. (JP) 1983-08-09 US disclosed
JP-S5756438-A 3-PHENOXYBENZYL 2-(4-CHLOROPHENYL)-2-METHYLPROPYL ETHER, ITS PREPARATION, AND INSECTICIDAL MITICIDAL AGENT HAVING LOW TOXICITY TO FISH AND CONTAINING SAID COMPOUND MITSUI TOATSU CHEM INC 1982-04-05 JP disclosed