Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 5/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029704 | 0.93 | PPARA (0.34) | PPARAPPARGALOX5 | |
| SCHEMBL9030891 | 0.92 | PPARA (0.40) | PPARAPPARGALOX5CYP4F2CYP4A11 | |
| SCHEMBL9031371 | 0.88 | ALOX5 (0.38) | PPARAPPARGALOX5CYP4F2CYP4A11 | |
| SCHEMBL9030239 | 0.86 | PPARA (0.39) | PPARAPPARGALOX5CYP4F2CYP4A11 | |
| SCHEMBL9769521 | 0.86 | CYP4F2 (0.42) | PPARAPPARGALOX5CYP4F2CYP4A11 | |
| SCHEMBL9029933 | 0.85 | ALOX5 (0.36) | PPARAPPARGALOX5 | |
| SCHEMBL9029711 | 0.85 | PPARG (0.36) | PPARAPPARGCYP4F2CYP4A11 | |
| SCHEMBL9030826 | 0.85 | ALOX5 (0.35) | PPARAPPARGALOX5 | |
| SCHEMBL9029432 | 0.84 | ALOX5 (0.35) | PPARAPPARGALOX5 | |
| SCHEMBL9031163 | 0.82 | PPARG (0.37) | PPARAPPARGCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513285-B1 | IMIDAZOL-2-YL DERIVATIVES OF SUBSTITUTED BICYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION | PHARMACIA SPA (IT) | 1996-01-24 | — | — | EP | claimed |
| EP-0513285-B1 | IMIDAZOL-2-YL DERIVATIVES OF SUBSTITUTED BICYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION | PHARMACIA SPA (IT) | 1996-01-24 | — | — | EP | disclosed |
| US-5356920-A | Anticholesterol, antilipemic agent | FARMITALIA CARLO ERBA SRL. (IT) | 1994-10-18 | — | — | US | disclosed |