Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 5/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9030891 | 0.94 | PPARA (0.40) | PPARAPPARGLTB4RALOX5CYP4F2 | |
| SCHEMBL9029722 | 0.93 | PPARG (0.34) | PPARAPPARGALOX5NFKB1NFKB2 | |
| SCHEMBL9029953 | 0.89 | PPARG (0.32) | PPARGALOX5NFKB1NFKB2RELA | |
| SCHEMBL9029933 | 0.88 | ALOX5 (0.36) | PPARAPPARGALOX5 | |
| SCHEMBL9029711 | 0.88 | PPARG (0.36) | PPARAPPARGCYP4F2CYP4A11S1PR1 | |
| SCHEMBL9675661 | 0.87 | NFKB1 (0.33) | PPARGALOX5NFKB1NFKB2RELA | |
| SCHEMBL9030826 | 0.87 | ALOX5 (0.35) | PPARAPPARGALOX5S1PR1S1PR3 | |
| SCHEMBL9030642 | 0.87 | NAAA (0.30) | — | |
| SCHEMBL9029432 | 0.87 | ALOX5 (0.35) | PPARAPPARGALOX5 | |
| SCHEMBL9030263 | 0.86 | PPARA (0.41) | PPARAPPARGLTB4RALOX5CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513285-B1 | IMIDAZOL-2-YL DERIVATIVES OF SUBSTITUTED BICYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION | PHARMACIA SPA (IT) | 1996-01-24 | — | — | EP | claimed |