Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NAAA | Q02083 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 3/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5540645 | 0.90 | MAPK1 (0.58) | ALDH1A1F10PRSS1ITGB3ITGA2B | |
| SCHEMBL14599582 | 0.88 | MAPK1 (0.61) | L3MBTL1NAAAALDH1A1F10PRSS1 | |
| SCHEMBL14599618 | 0.88 | MAPK1 (0.61) | L3MBTL1NAAAALDH1A1F10PRSS1 | |
| SCHEMBL14599581 | 0.88 | MAPK1 (0.61) | L3MBTL1NAAAALDH1A1F10PRSS1 | |
| SCHEMBL14599527 | 0.88 | MAPK1 (0.61) | L3MBTL1NAAAALDH1A1F10PRSS1 | |
| SCHEMBL28326194 | 0.88 | L3MBTL1 (0.73) | L3MBTL1SMN1; SMN2NAAACA2MLYCD | |
| SCHEMBL2967223 | 0.86 | L3MBTL1 (0.63) | L3MBTL1SMN1; SMN2NAAACA2MLYCD | |
| SCHEMBL14519316 | 0.84 | NPC1 (0.54) | L3MBTL1NAAACA2MLYCDALDH1A1 | |
| SCHEMBL5940563 | 0.83 | LMNA (0.64) | L3MBTL1SMN1; SMN2NAAACA2MLYCD | |
| SCHEMBL5072880 | 0.81 | L3MBTL1 (0.71) | L3MBTL1SMN1; SMN2NAAACA2MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |