Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.53 |
| ▸ | F10 | P00742 | 13/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | KLK8 | O60259 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | KLK2 | P20151 | 1/20 | 0.42 |
| ▸ | KLK4 | Q9Y5K2 | 1/20 | 0.42 |
| ▸ | MASP2 | O00187 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9030444 | 0.79 | PRSS1 (0.48) | F2F10PRSS1PLAUPLG | |
| SCHEMBL8174692 | 0.78 | F2 (0.42) | F2F10PRSS1PLAU | |
| SCHEMBL8556445 | 0.76 | PRSS1 (0.52) | F2F10PRSS1PLAUPLG | |
| SCHEMBL9029742 | 0.76 | F2 (0.43) | F2F10PRSS1TPSAB1ITGB3 | |
| SCHEMBL8173801 | 0.76 | F7 (0.47) | F2F10PRSS1TPSAB1PLAU | |
| SCHEMBL9031211 | 0.75 | F10 (0.48) | F2F10PRSS1 | |
| SCHEMBL8169531 | 0.75 | F2 (0.40) | F2F10PRSS1PLAUPLG | |
| SCHEMBL8174677 | 0.74 | TPSAB1 (0.39) | TPSAB1 | |
| SCHEMBL9030101 | 0.72 | ALDH1A1 (0.49) | F2F10PRSS1TPSAB1 | |
| SCHEMBL8560464 | 0.72 | C3AR1 (0.39) | F10PRSS1TPSAB1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |