SCHEMBL9030583

SCHEMBL9030583

CC(C)=CC1C(C(=O)CN2C(=O)C3=C(CCCC3)C2=O)C1(C)C

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.40
TSHR P16473 3/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CYP1A2 P05177 2/20 0.34
CYP2C19 P33261 2/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
TRPV1 Q8NER1 1/20 0.34
HPGD P15428 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALOX15 P16050 1/20 0.31
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetramethrin SCHEMBL22714265 0.81 LMNA (0.56) LMNATSHRNPSR1CYP1A2CYP2C19
(1R)-Trans-Tetramethrin SCHEMBL2973441 0.81 LMNA (0.56) LMNATSHRNPSR1CYP1A2CYP2C19
Tetramethrin SCHEMBL7926801 0.81 LMNA (0.56) LMNATSHRNPSR1CYP1A2CYP2C19
Tetramethrin SCHEMBL5883725 0.80 LMNA (0.52) LMNATSHRNPSR1CYP1A2CYP2C19
Tetramethrin SCHEMBL28849516 0.77 LMNA (0.53) LMNATSHRCYP1A2CYP2C19CYP3A4
SCHEMBL10998002 0.74 LMNA (0.34) LMNATSHRCYP1A2CYP2C19ALOX15
Tetramethrin SCHEMBL4422842 0.73 LMNA (0.46) LMNATSHRNPSR1CYP1A2CYP2C19
SCHEMBL11625926 0.70 LMNA (0.45) LMNATSHRCYP1A2CYP2C19CYP3A4
SCHEMBL13198752 0.69 LMNA (0.47) LMNATSHRCYP1A2CYP2C19CYP3A4
SCHEMBL8321402 0.69 LMNA (0.55) LMNATSHRNPSR1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0490323-B1 Imidazolidine derivatives, preparation thereof, insecticides containing same as an effective ingredient and intermediates therefor MITSUI TOATSU CHEMICALS (JP) 1996-05-01 EP disclosed
EP-0455000-B1 Dialkoxymethylimidazolidine derivatives, preparation thereof, insecticides containing same as an effective ingredient and intermediates therefor MITSUI TOATSU CHEMICALS (JP) 1996-01-31 EP disclosed
EP-0547557-B1 N-vinylimidazolidine derivatives, preparation thereof, insecticides containing same as an effective ingredient and intermediates thereof MITSUI TOATSU CHEMICALS (JP) 1994-07-27 EP disclosed
US-5310920-A N-vinylimidazolidine derivatives insecticides containing same as an effective ingredient MITSUI TOATSU CHEMICALS, INC. (JP) 1994-05-10 US disclosed
US-5264584-A Dialkoxymethylimidazolidine derivatives MITSUI TOATSU CHEMICALS, INC. (JP) 1993-11-23 US disclosed
EP-0547557-A1 N-vinylimidazolidine derivatives, preparation thereof, insecticides containing same as an effective ingredient and intermediates thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-06-23 EP disclosed
US-5219868-A Insecticides MITSUI TOATSU CHEMICALS, INC. (JP) 1993-06-15 US disclosed
US-5192778-A DIALKOXYMETHYLIMIDAZOLIDINE DERIVATIVES, PREPARATION THEREOF, INSECTICIDES CONTAINING SAME AS AN EFFECTIVE INGREDIENT AND INTERMEDIATES THEREFOR MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-09 US disclosed
EP-0490323-A1 Imidazolidine derivatives, preparation thereof, insecticides containing same as an effective ingredient and intermediates therefor MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-06-17 EP disclosed
EP-0455000-A1 Dialkoxymethylimidazolidine derivatives, preparation thereof, insecticides containing same as an effective ingredient and intermediates therefor MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-11-06 EP disclosed
US-4814340-A 1,4-diaryl alkane derivatives having insecticidal and acaricidal activity MITSUI TOATSU CHEMICALS, INC. (JP) 1989-03-21 US disclosed
US-4782094-A Difluorobromomethoxyphenyl derivative and miticide comprising said derivative as active ingredient MITSUI TOATSU CHEMICALS, INC. (JP) 1988-11-01 US disclosed
US-4661501-A Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity MITSUI TOATSU CHEMICALS, INC. (JP) 1987-04-28 US disclosed
EP-0207728-A2 Novel pyrazoline compounds, process for production thereof, and insecticides containing them as active ingredients MITSUI TOATSU CHEMICALS, Inc. (JP) 1987-01-07 EP disclosed
US-4599362-A 2-aryl-ethyl ether derivatives and insecticidal and acaricidal agents containing said derivatives MITSUITOATSU CHEMICALS, INC. (JP) 1986-07-08 US disclosed
US-4570005-A REACTING THE ARYL PROPYL CHLORIDE WITH THE CORRESPONDING ARYL ALCOHOL OR ARYL MERCAPTAN MITSUITOATSU CHEMICALS INC. (JP) 1986-02-11 US disclosed
US-4397864-A LOW TOXICITY MITSUITOATSU CHEMICALS INC. (JP) 1983-08-09 US disclosed
US-4293504-A Process for preparing optically active α-cyano-3-(4-halogenophenoxy)-benzyl 2-(4-chlorophenyl)isovalerate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-10-06 US disclosed
US-4279924-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-07-21 US disclosed