Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9030621 | 1.00 | PGR (0.35) | PGRARMAPTMEN1POLB | |
| SCHEMBL9030022 | 0.84 | PNMT (0.37) | MAPTMEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL9030012 | 0.84 | PNMT (0.37) | MAPTMEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL9031231 | 0.83 | AKR1B1 (0.36) | MAPTMEN1POLBKMT2AMCL1 | |
| SCHEMBL9031240 | 0.83 | AKR1B1 (0.36) | MAPTMEN1POLBKMT2AMCL1 | |
| SCHEMBL7389556 | 0.77 | CHRNB4 (0.40) | MAPTMEN1POLBKMT2AL3MBTL1 | |
| SCHEMBL9030228 | 0.77 | CHRNB4 (0.40) | MAPTMEN1POLBKMT2AL3MBTL1 | |
| SCHEMBL9030857 | 0.75 | AR (0.43) | PGRARMAPTATMTDP1 | |
| SCHEMBL9029949 | 0.75 | AR (0.33) | AR | |
| SCHEMBL9029956 | 0.75 | AR (0.33) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0732334-A1 | Piperidine derivatives, process for their preparation and their therapeutic application | SYNTHELABO (FR) | 1996-09-18 | — | — | EP | disclosed |