SCHEMBL9030642

SCHEMBL9030642

CC(C)c1cccc(C(C)C)c1NC(=O)C(C)(C)CCCOc1ccc2c(c1)OC(CCc1ccccc1)C(c1nccn1C)=C2

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.30
FFAR1 O14842 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9030365 0.95 ALOX5 (0.34) NAAAFFAR1
SCHEMBL4984395 0.89 EPHX2 (0.32)
SCHEMBL9030239 0.87 PPARA (0.39)
SCHEMBL9030559 0.84
SCHEMBL9029722 0.84 PPARG (0.34) NAAA
SCHEMBL9029661 0.84 KDM4E (0.41)
SCHEMBL9030164 0.84 ALOX5 (0.34) FFAR1
SCHEMBL9030891 0.82 PPARA (0.40)
SCHEMBL9029953 0.81 PPARG (0.32)
SCHEMBL9029741 0.81 KMT2A (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0513285-B1 IMIDAZOL-2-YL DERIVATIVES OF SUBSTITUTED BICYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION PHARMACIA SPA (IT) 1996-01-24 EP disclosed
US-5356920-A Anticholesterol, antilipemic agent FARMITALIA CARLO ERBA SRL. (IT) 1994-10-18 US disclosed