Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | FPR1 | P21462 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6908195 | 1.00 | RAB9A (0.49) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL6905018 | 0.93 | SMN1; SMN2 (0.48) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL6908080 | 0.89 | RAB9A (0.45) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL6906796 | 0.88 | SMN1; SMN2 (0.48) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL6906802 | 0.88 | SMN1; SMN2 (0.48) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL6905976 | 0.88 | SMN1; SMN2 (0.48) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL6903793 | 0.88 | SMN1; SMN2 (0.48) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL6905863 | 0.84 | FPR1 (0.51) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL9032753 | 0.84 | FPR1 (0.51) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL6908592 | 0.83 | FPR1 (0.45) | RAB9ASMN1; SMN2NPC1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706514-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995006034-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1995-03-02 | — | — | WO | disclosed |