Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 7/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.51 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 3/20 | 0.50 |
| ▸ | PLG | P00747 | 2/20 | 0.50 |
| ▸ | PLAT | P00750 | 2/20 | 0.50 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.50 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.50 |
| ▸ | KLK8 | O60259 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | KLK4 | Q9Y5K2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029750 | 0.88 | F2 (0.53) | KMT2AF2PRSS1PRSS2PRSS3 | |
| SCHEMBL9328838 | 0.84 | KMT2A (0.65) | MEN1HTTGFERKMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL9488543 | 0.83 | KMT2A (0.63) | MEN1HTTGFERKMT2AHSD17B10 | |
| SCHEMBL697595 | 0.82 | KMT2A (0.60) | MEN1HTTGFERKMT2AHSD17B10 | |
| SCHEMBL9328632 | 0.82 | KMT2A (0.55) | MEN1HTTGFERKMT2AHSD17B10 | |
| SCHEMBL15242478 | 0.82 | MAOB (0.67) | MEN1HTTGFERKMT2AHSD17B10 | |
| SCHEMBL5654161 | 0.81 | RAB9A (0.56) | MEN1HTTGFERKMT2AHSD17B10 | |
| SCHEMBL8173802 | 0.81 | KMT2A (0.71) | MEN1KMT2AF2PLAUPLG | |
| SCHEMBL1927968 | 0.81 | LMNA (0.59) | MEN1HTTGFERKMT2AHSD17B10 | |
| SCHEMBL9511809 | 0.81 | KMT2A (0.60) | MEN1HTTGFERKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |