Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.55 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9650651 | 0.80 | PRSS1 (0.81) | PRSS1PRSS2PRSS3TMPRSS2RAB9A | |
| SCHEMBL9030824 | 0.79 | MRGPRX1 (0.57) | PRSS1PRSS2PRSS3TMPRSS2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11182186 | 0.78 | PRSS1 (0.82) | PRSS1PRSS2PRSS3TMPRSS2RAB9A | |
| SCHEMBL8555919 | 0.78 | MRGPRX1 (0.46) | PRSS1PRSS2PRSS3ALDH1A1LMNA | |
| SCHEMBL7571948 | 0.77 | PRSS1 (0.82) | PRSS1PRSS2PRSS3TMPRSS2LMNA | |
| Hydrochloric Acid SCHEMBL28283096 | 0.77 | PRSS1 (0.76) | PRSS1PRSS2PRSS3TMPRSS2RAB9A | |
| SCHEMBL9030764 | 0.77 | MRGPRX1 (0.45) | PRSS1PRSS2PRSS3SMN1; SMN2MRGPRX1 | |
| Hydrochloric Acid SCHEMBL11610062 | 0.75 | PRSS1 (0.83) | PRSS1PRSS2PRSS3TMPRSS2LMNA | |
| SCHEMBL9650565 | 0.75 | PRMT1 (0.83) | PRSS1PRSS2PRSS3TMPRSS2LMNA | |
| SCHEMBL9649959 | 0.75 | PRMT1 (0.83) | PRSS1PRSS2PRSS3TMPRSS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |