Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9030758 | 1.00 | CETP (0.43) | CETPCSNK1ECTRCCNR2CTSK | |
| SCHEMBL16667474 | 1.00 | CETP (0.43) | CETPCSNK1ECTRCCNR2CTSK | |
| SCHEMBL11731022 | 0.99 | CETP (0.41) | CETPCSNK1ECTRCCNR2CTSK | |
| SCHEMBL11731029 | 0.99 | CETP (0.41) | CETPCSNK1ECTRCCNR2CTSK | |
| SCHEMBL3426595 | 0.87 | TSHR (0.44) | CETPCSNK1ECTRCCNR2EPHX2 | |
| SCHEMBL9685558 | 0.86 | BCHE (0.42) | CETPCSNK1ECTRCCNR2 | |
| SCHEMBL9684154 | 0.86 | BCHE (0.42) | CETPCSNK1ECTRCCNR2 | |
| SCHEMBL9685612 | 0.86 | BCHE (0.42) | CETPCSNK1ECTRCCNR2 | |
| SCHEMBL13030082 | 0.85 | TBXAS1 (0.41) | CNR2CTSK | |
| SCHEMBL28998085 | 0.83 | CETP (0.45) | CETPCSNK1ECTRCCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134230-A | Disaccharide Antitumor Agent Intermediates | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-07-28 | — | — | US | claimed |
| EP-2280007-B1 | THE PREPARATION METHOD OF (3S,4S)-3-HEXYL-4-((R)-2-HYDROXYTRIDECYL)-OXETAN-2-ONE AND THE PRODUCT OF THAT METHOD | CHONGQING ZHIEN PHARMACEUTICAL CO LTD (CN) | 2015-04-29 | — | — | EP | disclosed |
| EP-0444482-B1 | Oxetanones | HOFFMANN LA ROCHE (CH) | 1996-01-17 | — | — | EP | disclosed |
| US-5466708-A | Carbamyloxyoxetanone compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-11-14 | — | — | US | disclosed |
| US-5376674-A | Lipase inhibitors | HOFFMAN-LA ROCHE INC. (US) | 1994-12-27 | — | — | US | disclosed |
| US-5260310-A | Oxetanone compounds and pharmaceutical compositions containing them | HOFFMANN-LA ROCHE INC. (US) | 1993-11-09 | — | — | US | disclosed |
| EP-0444482-A2 | Oxetanones | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-04 | — | — | EP | disclosed |