Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685558 | 1.00 | BCHE (0.42) | BCHEACHECETPCSNK1EMEN1 | |
| SCHEMBL9684154 | 1.00 | BCHE (0.42) | BCHEACHECETPCSNK1EMEN1 | |
| SCHEMBL16177752 | 0.94 | BCHE (0.39) | BCHEACHECETPCNR2ALDH1A1 | |
| SCHEMBL9685360 | 0.87 | MAPT (0.39) | BCHE | |
| SCHEMBL9030758 | 0.86 | CETP (0.43) | CETPCSNK1ECTRCCNR2 | |
| SCHEMBL9030769 | 0.86 | CETP (0.43) | CETPCSNK1ECTRCCNR2 | |
| SCHEMBL16667474 | 0.86 | CETP (0.43) | CETPCSNK1ECTRCCNR2 | |
| SCHEMBL9577155 | 0.85 | SMN1; SMN2 (0.41) | BCHEMEN1KMT2A | |
| SCHEMBL9497399 | 0.85 | SMN1; SMN2 (0.41) | BCHEMEN1KMT2A | |
| SCHEMBL17006171 | 0.84 | LTA4H (0.38) | BCHEMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145844-A | Enzyme inhibitors, antiinflammatory agents, analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-09-08 | — | — | US | disclosed |
| US-5030733-A | Analgesics, antiinflammatory agents, phospholipase inhibitor | HOECHST-ROUSSEL PHARMACETICALS INCORPORATED (US) | 1991-07-09 | — | — | US | disclosed |
| EP-0300397-A2 | Hydroxy-, Alkoxy- and Benzyloxy substituted phospholipids, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-01-25 | — | — | EP | disclosed |