Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032028 | 0.95 | KMT2A (0.45) | AGTR1KMT2AAGTR2 | |
| SCHEMBL9033049 | 0.94 | KMT2A (0.42) | AGTR1KMT2A | |
| SCHEMBL9032837 | 0.94 | AGTR1 (0.43) | AGTR1KMT2AMEN1AGTR2TSHR | |
| SCHEMBL9030640 | 0.94 | AGTR1 (0.42) | AGTR1 | |
| SCHEMBL9032380 | 0.93 | AGTR1 (0.42) | AGTR1 | |
| SCHEMBL9032254 | 0.92 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9033155 | 0.90 | AGTR1 (0.41) | AGTR1 | |
| SCHEMBL9032491 | 0.89 | POLB (0.41) | AGTR1 | |
| SCHEMBL9032218 | 0.88 | CXCL8 (0.40) | AGTR1 | |
| SCHEMBL9031501 | 0.88 | KMT2A (0.42) | AGTR1KMT2AAGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483683-B1 | Thienoimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5463073-A | Angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0483683-A2 | Thienoimidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-05-06 | — | — | EP | disclosed |