Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GNRHR | P30968 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427196 | 0.85 | STAT3 (0.52) | STAT3HTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL9031356 | 0.84 | STAT3 (0.53) | STAT3HTTTSHRCASP1KDM4E | |
| SCHEMBL3290751 | 0.79 | STAT3 (0.41) | STAT3HTTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL27287068 | 0.74 | STAT3 (0.70) | STAT3HTTTSHRCASP1KDM4E | |
| SCHEMBL9427167 | 0.73 | STAT3 (0.38) | STAT3HTTKDM4EALDH1A1RECQL | |
| SCHEMBL9030909 | 0.72 | STAT3 (0.67) | STAT3HTTTSHRCASP1KDM4E | |
| SCHEMBL13326854 | 0.72 | STAT3 (0.48) | STAT3HTTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL10899205 | 0.72 | KDM4E (0.44) | STAT3KDM4EALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL23646765 | 0.71 | LMNA (0.44) | TSHRKDM4EALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL1345146 | 0.71 | STAT3 (0.65) | STAT3HTTTSHRCASP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470578-B1 | Novel tricyclic compound or salts thereof, method for producing the same and antimicrobial agent containing the same | WAKUNAGA SEIYAKU KK (JP) | 1996-11-06 | — | — | EP | disclosed |
| US-5399553-A | Oral absorbability | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-03-21 | — | — | US | disclosed |
| US-5359066-A | Certain tricyclic pyrido[3,2,1-ij]cinnoline-8-carboxylates, useful as antimicrobial agents | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| US-5254685-A | Tricyclic compound or salts thereof, method for producing the same and antimicrobial agent containing the same | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-10-19 | — | — | US | disclosed |
| EP-0530368-A1 | PROCESS FOR PRODUCING TRICYCLIC COMPOUND OR SALT THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-10 | — | — | EP | disclosed |
| CN-1059144-A | New tricyclic compound or its salt, prepare their method and contain their antiseptic-germicide | WAKUNAGA SEIYAKU KK (JP) | 1992-03-04 | — | — | CN | disclosed |
| EP-0470578-A1 | Novel tricyclic compound or salts thereof, method for producing the same and antimicrobial agent containing the same | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1992-02-12 | — | — | EP | disclosed |