Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27722453 | 0.86 | KMT2A (0.76) | KMT2AMEN1GAASMN1; SMN2MAPK1 | |
| SCHEMBL316093 | 0.86 | KMT2A (0.76) | KMT2AMEN1GAASMN1; SMN2MAPK1 | |
| SCHEMBL1574735 | 0.85 | KMT2A (0.73) | KMT2AMEN1GAASMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL4846563 | 0.85 | KMT2A (0.73) | KMT2AMEN1GAASMN1; SMN2MAPK1 | |
| SCHEMBL903110 | 0.83 | KMT2A (1.00) | KMT2AMEN1GAASMN1; SMN2MAPK1 | |
| SCHEMBL892042 | 0.83 | KMT2A (0.71) | KMT2AMEN1GAASMN1; SMN2MAPK1 | |
| SCHEMBL6241386 | 0.83 | GAA (0.71) | KMT2AMEN1GAASMN1; SMN2MAPK1 | |
| SCHEMBL10929681 | 0.83 | KMT2A (0.71) | KMT2AMEN1GAASMN1; SMN2MAPK1 | |
| SCHEMBL1260007 | 0.83 | KMT2A (0.71) | KMT2AMEN1GAASMN1; SMN2MAPK1 | |
| SCHEMBL10929688 | 0.83 | KMT2A (0.62) | KMT2AMEN1GAASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040494-B1 | CARBAPENAMS AND CARBAPEN-2-EMS AND PROCESS THEREFOR | PFIZER INC. (US) | 1984-02-15 | — | — | EP | claimed |
| US-4429128-A | CARBAPENICILLINS, THIENAMYCINS, BACTERICIDES | PFIZER INC. (US) | 1984-01-31 | — | — | US | claimed |
| US-4407815-A | AMINO ACID DERIVATIVE ANTIBIOTICS | BEECHAM GROUP LIMITED (GB) | 1983-10-04 | — | — | US | claimed |
| US-4348264-A | Photocatalyzed process for producing carbapenams and carbapen-2-ems | PFIZER INC. (US) | 1982-09-07 | — | — | US | claimed |
| EP-0040494-A1 | Carbapenams and carbapen-2-ems and process therefor | PFIZER INC. (US) | 1981-11-25 | — | — | EP | claimed |
| US-3989685-A | FROM PENICILLIN-1-OXIDE | SHINOGI & CO., LTD. (JA) | 1976-11-02 | — | — | US | claimed |
| EP-1265857-A1 | SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001068592-A1 | SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-09-20 | — | — | WO | disclosed |
| US-5750735-A | CHEMICAL INTERMEDIATES FOR ANTIBIOTICS | AMERICAN CYANAMID COMPANY (US) | 1998-05-12 | — | — | US | disclosed |
| US-5744465-A | Method of inhibiting a β-lactamase enzyme by administering novel 2-thiosubstituted carbapenems | AMERICAN CYANAMID COMPANY (US) | 1998-04-28 | — | — | US | disclosed |
| EP-0504612-B1 | Novel 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID CO (US) | 1998-01-21 | — | — | EP | disclosed |
| US-5700930-A | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1997-12-23 | — | — | US | disclosed |
| US-5656753-A | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them | AMERICAN CYANAMID COMPANY (US) | 1997-08-12 | — | — | US | disclosed |
| US-4387051-A | β-Lactam antibiotics, their preparation and their use in pharmaceutical compositions | BEECHAM GROUP LIMITED (GB) | 1983-06-07 | — | — | US | disclosed |
| EP-0073100-A1 | Beta-lactam compounds, their preparation and their use | BEECHAM GROUP PLC (GB) | 1983-03-02 | — | — | EP | disclosed |
| EP-0067518-A1 | Modified beta-lactam compounds | BEECHAM GROUP PLC (GB) | 1982-12-22 | — | — | EP | disclosed |
| US-4348264-A | Photocatalyzed process for producing carbapenams and carbapen-2-ems | PFIZER INC. (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0040494-A1 | Carbapenams and carbapen-2-ems and process therefor | PFIZER INC. (US) | 1981-11-25 | — | — | EP | disclosed |
| EP-0034443-A2 | Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1981-08-26 | — | — | EP | disclosed |
| EP-0028497-A1 | Beta-lactam antibiotics, their preparation and their use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-05-13 | — | — | EP | disclosed |