⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4824016 | 0.80 | — | — | |
| SCHEMBL5457200 | 0.78 | FBP1 (1.00) | — | |
| SCHEMBL8878345 | 0.78 | FBP1 (0.70) | — | |
| SCHEMBL10359781 | 0.69 | FBP1 (0.50) | — | |
| SCHEMBL10388109 | 0.69 | FBP1 (0.50) | — | |
| SCHEMBL11337819 | 0.68 | FBP1 (0.48) | — | |
| SCHEMBL11281498 | 0.66 | FBP1 (0.47) | — | |
| SCHEMBL17726992 | 0.66 | FBP1 (0.47) | — | |
| SCHEMBL2211934 | 0.63 | SMN1; SMN2 (0.56) | — | |
| SCHEMBL12949409 | 0.63 | FBP1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681224-A1 | DEGRADATION OF PENICILLIN COMPOUNDS | DSM Sinochem Pharmaceuticals Netherlands B.V. (NL) | 2014-01-08 | — | — | EP | claimed |
| WO-2012117038-A1 | DEGRADATION OF PENICILLIN COMPOUNDS | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2012-09-07 | — | — | WO | claimed |
| US-20100267555-A1 | Fungicidal mixtures II | BASF SE (DE) | 2010-10-21 | — | — | US | claimed |
| WO-2004101572-A1 | 7-GLUTARYL IMIDE CEPHALOSPORANIC ACID DERIVATIVES AND PROCESS FOR PREPARING IT | CKD BIO CORPORATION (KR) | 2004-11-25 | — | — | WO | claimed |
| US-6420554-B1 | REACTION OF BETA LACTAM WITH PHOSPHOROUS HALIDE IN THE PRESENCE OF BASE, ADDING PHENOL, REACTION WITH ALCOHOL AND REMOVAL OF ESTER | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2002-07-16 | — | — | US | claimed |
| EP-0440959-B1 | Process for the preparation of 2-alkylthio-1,3,4-thiadiazoles | BAYER AG (DE) | 1994-02-16 | — | — | EP | claimed |
| EP-0188254-B1 | CEPHEM COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-24 | — | — | EP | claimed |
| US-4761410-A | MICROBIOCIDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-02 | — | — | US | claimed |
| US-4729991-A | SUBSTITUTED BY HETEROCYCLIC THIOMETHYL GROUP | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-08 | — | — | US | claimed |
| US-4605651-A | BACTERICIDES | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1986-08-12 | — | — | US | claimed |
| EP-0075434-A2 | Cephalosporins, their preparation and their pharmaceutical compositions | ICI PHARMA (FR) | 1983-03-30 | — | — | EP | claimed |
| EP-0055562-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1982-07-07 | — | — | EP | claimed |
| US-4331664-A | BACTERIOSTATS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-05-25 | — | — | US | claimed |
| US-4268509-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-05-19 | — | — | US | claimed |
| US-4267176-A | Amino or acylamino-substituted pyrimidinyl cephalosporanic acid derivatives and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-05-12 | — | — | US | claimed |
| US-4200747-A | 7-2-Indolyl acetamido cephalosporin derivatives | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1980-04-29 | — | — | US | claimed |
| EP-0007470-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-06 | — | — | EP | claimed |
| US-4154831-A | Cephalosporins having an α-acylaminoacetic acid side chain | CIBA-GEIGY CORPORATION (US) | 1979-05-15 | — | — | US | claimed |
| US-4068071-A | DISULFIDING, SOLVOLYSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-01-10 | — | — | US | claimed |
| US-4068072-A | CHLORINATION OR BROMINATION, SOLVOLYSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-01-10 | — | — | US | claimed |