SCHEMBL2211934

SCHEMBL2211934

c1ccc(CSc2nncs2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.56
HPGD P15428 2/20 0.56
ALDH1A1 P00352 5/20 0.54
MAPK1 P28482 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.52
GAA P10253 1/20 0.52
LMNA P02545 2/20 0.49
FBP1 P09467 1/20 0.48
MAPT P10636 2/20 0.46
HSD17B10 Q99714 1/20 0.46
CDK2 P24941 1/20 0.45
USP2 O75604 1/20 0.44
CDK1 P06493 1/20 0.44
CCNB1 P14635 1/20 0.44
FFAR1 O14842 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
CA1 P00915 1/20 0.43
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11299725 0.80 HPGD (0.64) SMN1; SMN2HPGDALDH1A1L3MBTL1GAA
SCHEMBL9593421 0.80 NPC1 (0.45) SMN1; SMN2HPGDALDH1A1MAPK1L3MBTL1
SCHEMBL3263155 0.78 LMNA (0.72) SMN1; SMN2HPGDALDH1A1MAPK1GAA
SCHEMBL22792065 0.76 ALDH1A1 (0.57) SMN1; SMN2HPGDALDH1A1MAPK1L3MBTL1
SCHEMBL9127784 0.75 ALDH1A1 (0.49) SMN1; SMN2HPGDALDH1A1MAPK1L3MBTL1
SCHEMBL24700466 0.73 LMNA (0.66) SMN1; SMN2HPGDALDH1A1MAPK1GAA
SCHEMBL23137230 0.73 LMNA (0.66) SMN1; SMN2HPGDALDH1A1MAPK1GAA
SCHEMBL9362368 0.72 L3MBTL1 (0.50) SMN1; SMN2HPGDALDH1A1MAPK1L3MBTL1
SCHEMBL6492979 0.70 MEN1 (0.59) SMN1; SMN2HPGDALDH1A1MAPK1L3MBTL1
SCHEMBL23137231 0.70 LMNA (0.62) SMN1; SMN2HPGDALDH1A1MAPK1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109134548-A Aryl ruthenium complex and the preparation method and application thereof for treating liver cancer 广西师范学院 2019-01-04 CN claimed
EP-1952918-B1 METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM TOYO INK MFG CO (JP) 2013-05-22 EP disclosed
US-8440110-B2 Method for producing metal particle dispersion, conductive ink using metal particle dispersion produced by such method, and conductive coating film TOYO INK MFG CO., LTD. (JP) 2013-05-14 US disclosed
US-20110175040-A1 METHOD FOR PRODUCING METAL PARTICLE DISPRESION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM TOYO INK MFG CO., LTD. (JP) 2011-07-21 US disclosed
US-7981327-B2 Method for producing metal particle dispersion, conductive ink using metal particle dispersion produced by such method, and conductive coating film TOYO INK MFG. CO. LTD. (JP) 2011-07-19 US disclosed
US-20090258202-A1 Method for Producing Metal Particle Dispersion, Conductive Ink Using Metal Particle Dispersion Produced by Such Method, and Conductive Coating Film GVP GESELLSCHAFT ZUR VERMARKTUNG DER PORENBRENNERTECHNIK MBH (DE) 2009-10-15 US disclosed
EP-1952918-A1 METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM Toyo Ink Mfg. Co., Ltd (JP) 2008-08-06 EP disclosed
EP-0579129-B1 Thiadiazole derivatives for the treatment of depressive states CT LAB FARM SRL (IT) 1997-03-05 EP disclosed
EP-0579129-A2 Thiadiazole derivatives for the treatment of depressive states LABORATORIO FARMACEUTICO C.T. S.r.l. (IT) 1994-01-19 EP disclosed
EP-0396201-A1 Thiadiazoline-sulphonamides useful for the treatment of glaucoma Trager, Seymour F. (US) 1990-11-07 EP disclosed
US-4883880-A Process for the preparation of sulfoalkyl quaternary salts and for the production of alkane sultones AGFA-GEVAERT AKTIENGESSELLSCHAFT (DE) 1989-11-28 US disclosed
US-4539408-A Process for the preparation of sulphoalkyl quaternary salts AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1985-09-03 US disclosed
EP-0064667-B1 PROCESS FOR THE PREPARATION OF SULFOALKYL QUATERNARY SALTS Agfa-Gevaert AG (DE) 1984-11-28 EP disclosed
EP-0055428-B1 BIS-(3-SULFOPROPYL)ETHERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ALKYLATING AGENTS FOR ORGANIC BASES Agfa-Gevaert AG (DE) 1984-03-14 EP disclosed
EP-0064667-A1 Process for the preparation of sulfoalkyl quaternary salts Agfa-Gevaert AG (DE) 1982-11-17 EP disclosed
EP-0055428-A1 Bis-(3-sulfopropyl)ethers, process for their preparation and their use as alkylating agents for organic bases Agfa-Gevaert AG (DE) 1982-07-07 EP disclosed
US-4308390-A Process for the production of sulphoalkyl quaternary salts AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1981-12-29 US disclosed
US-4245033-A AN ORGANIC SILVER SALT, A HALIDE AND A SULFUR COMPOUND EXPOSED TO FORM A SILVER IMAGE OF HIGH CONTRAST AND STABILITY CANON KABUSHIKI KAISHA (JP) 1981-01-13 US disclosed
US-4217459-A POSTEMERGENCE HERBICIDES GULF OIL CORPORATION (US) 1980-08-12 US disclosed